二是优化生物样本采集要求。更新了监测人群的确定原则，新增了生物安全、采样空白、样本分装、样本接收、样本入库等关键环节的质量控制要求，并对血样和尿样的采集方式进行了调整优化，同时删减了脂肪、粪便、呼出气及其他组织等样本采集的相关内容。
The real annoying thing about Opus 4.6/Codex 5.3 is that it’s impossible to publicly say “Opus 4.5 (and the models that came after it) are an order of magnitude better than coding LLMs released just months before it” without sounding like an AI hype booster clickbaiting, but it’s the counterintuitive truth to my personal frustration. I have been trying to break this damn model by giving it complex tasks that would take me months to do by myself despite my coding pedigree but Opus and Codex keep doing them correctly. On Hacker News I was accused of said clickbaiting when making a similar statement with accusations of “I haven’t had success with Opus 4.5 so you must be lying.” The remedy to this skepticism is to provide more evidence in addition to greater checks and balances, but what can you do if people refuse to believe your evidence?
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